Multi-Layered Assembly For Hard Tissue Applications

Mrinal Bhattacharya, Professor
Tianhong Cui, Associate Professor, Mechanical Engineering
Dongjin Lee, Graduate Student, Mechanical Engineering

Objective

The objectives of this project include (i) develop composites of biodegradable aliphatic polyesters with an LBL assembly of chitosan and SWNT in varying concentrations to achieve the mechanical properties of bone, and (ii) study the effects of silanol (SiOH) functional groups through self-organized colloidal SiO2 on the surface of the biomaterial on the CaP deposition.

Need or Impact

Stress-shielding affects bone remodeling and the healing process, leading to increased bone porosity. These composites are expected to have properties (modulus) similar to that of human bone and thus reduce stress shielding.

Project Status

In progress.